Coffee and Migraine Headaches: Benefits and Drawbacks

The majority of migraineurs I see in my coaching practice are addicted to coffee.  And why not?  After all, coffee constricts blood vessels and thereby alleviates headache symptoms. There’s a good reason why caffeine is added as a key ingredient in some NSAID migraine meds like Excedrin: caffeine lowers adenosine levels (but like all other migraine meds as well as coffee itself, Excedrin also causes rebound headache). Coffee actually has a lot of great health benefits, some of them particularly relevant to those with migraine, which is probably one reason why so many with migraine are so dependent on it.  All of us also know that coffee consumption has some drawbacks as well – causing us to either feel physically or psychologically bad for drinking coffee when we do. So are coffee and migraine headaches incompatible, or complimentary?

Quite a few of us yo-yo between these two states: going through phases of intense coffee use and then denial, back and forth.  Others have wholeheartedly and without reservation accepted their coffee obsession, without any qualms.  A few lone souls have actually managed to completely stop drinking coffee.

Coffee is just too delicious and too sacred a ritual for the majority of my clients to give up with any ease.  Usually I will recommend that people NOT try to give up coffee in the early weeks of implementing the SimplyWell Migraine Relief Protocol because I think it is often unrealistic and too challenging to expect people to start drastically new dietary and lifetsyle habits while also going through withdrawal from their favorite drink.

But when we recognize we’ve reached a place where we are truly ready to do anything to heal, the time comes to really take stock of what we consume regularly, ESPECIALLY if our use of it is chronic, addictive, or we feel we literally can’t function without it.  That’s a sign that the substance offers substantial benefits but is also probably being misused.

Like all foods with inherently dynamic properties, there is ample evidence for both the benefits and drawbacks of coffee consumption as it relates to those with migraine.

Above all, my intention here is simply to share some of the research that I’ve found on both the positives and negatives of coffee and migraine headaches and how I personally choose to interface with coffee.  My intention here is neither to demonize or glorify coffee.  It’s a food grown from a plant, and you know how I adore plants.  I believe we need to be able to integrate food into our life while being very mindful and educated about each food’s properties, and then check in with our inner body wisdom and experience to make the final call about how much to incorporate that food into our life.

Coffee and caffeine’s affects on us are complex and vast. The most thorough and balanced article on coffee’s benefits and drawbacks that I was able to find concludes that much of the research on coffee is conflicting at best, because:

. . . most research studies observe and measure the effects of a single dose of caffeine rather than the effects of chronic ingestion. Yet most coffee drinkers drink coffee daily. As a number of studies have shown, single-dose experiments don’t necessarily reflect the effects of our regular routines. . .  [But what is clear is that] caffeine impacts whether certain chemicals are available; how receptive our brains are to them; and whether we’re even making those chemicals in the first place (Source).

Coffee benefits for those with migraine

Coffee imparts certain benefits to those with migraine especially.  The question is whether these short-term benefits are worth the drawbacks. So first, what’s so fabulous about coffee, above and beyond the taste and the ritual, specifically for those with migraine? Here are the highlights that I find intriguing:

  • “Chronic caffeine intake has been shown to increase the receptors of serotonin (26-30% increase), GABA (65% increase), and acetylcholine (40-50%). This may contribute to the elevated mood and perceived increase in energy we feel after a coffee.” (Source)
    Why this is relevant: Migraineurs tend to have lower levels of most neurotransmitters, including serotonin and acetylcholine, but more receptor sites for them (presumably because their levels are so low, they need more receptors to benefit from the few that are available). Coffee inadvertently increases receptivity to serotonin, GABA, and acetylcholine BECAUSE it depletes our bodies of them (maybe not such a good thing, but the initial effects of increased receptivity feel good).
    “In the human body, when neurotransmitter receptors . . . increase their sensitivity, it generally suggests a reduction in functional capacity and activity of neurons associated with those receptors. Either the brain needs more chemicals to do the job, or the neurons involved aren’t working as hard. This might mean that a certain neurotransmitter is in short supply, or that its activity needs to increase.” (Source)
  • Caffeine inhibits blood platelet aggregation (it does so by inhibiting the release of serotonin). Why this is relevant: Migraineurs generally have thick, sticky blood.
  • Caffeine synergizes with progesterone, and increases its concentration in blood and tissues. (Source)  Why this is relevant: progesterone is a glutamate scavenger.  It is also essential for the production of cortisol, which puts the brakes on histamine.  Progesterone offsets estrogen, an excessive amount of which contributes to histamine overload and interferes with proper signaling in your thyroid gland.  Increased progesterone can improve liver and thyroid function as well.  All of these are good things for those with migraine.
  • Coffee contains magnesium and potassium. Other vitamins and minerals found in coffee include vitamin K, riboflavin, niacin, folate, pantothenic acid, choline, calcium, phosphorus and manganese, but these are not present in dosages high enough to warrant drinking it. Why this is relevant: Migraineurs get migraines due in part to deficiencies in essential vitamins and electrolytes.
  • Caffeic acid, found in coffee as well as other plants like celery and the herb Danshen, lowers CGRP levels.  Why this is relevant: CGRP, an inflammatory neuropeptide, has shown to exist in higher levels in those with migraine.
  • Coffee raises blood pressure.  This is perhaps the greatest benefit of coffee, and explains why it can get rid of a headache once in awhile.  Coffee raises blood pressure by way of stimulating adrenaline. Why this is relevant:  those with migraine generally have low blood pressure, so raising it and thereby getting rid of the headache is a huge relief. The blood vessel constriction and raising of blood pressure results in reduced blood flow to the brain.  Check out these before and after images of the brain after coffee consumption.
  • “Caffeine affects the activity of a naturally occurring and necessary brain substance called adenosine. Adenosine levels in the blood go up during migraine attacks. Furthermore, adenosine when injected into a vein can trigger migraine attacks. Adenosine is widely available in the brain, and can produce many effects including less brain electrical activity, temporary widening of blood vessels, and control of some aspects of sleep and movement. Adenosine acts by sticking to specific receptor molecules on the surfaces of some brain cells. Caffeine can block the action of these receptors, and, thereby, stop the effects of adenosine. We do not know how these effects of caffeine result in acute anti-migraine and pain control actions.” (Source)
  •  Caffeine shows promise as a means to reduce β-amyloid levels which cause lesions in the brains of migraineurs and those with Alzheimer’s. So far, this has been demonstrated in transgenic mice.
  • Coffee is high in niacin.  One cup of coffee contains about 40 mg of niacin. Niacin helps to lower glutamate and increase blood flow in small capillaries of the body.

Coffee drawbacks for those with migraine

  • Despite increasing receptor sites for serotonin, caffeine inhibits the release of serotonin. Why this is relevant: low serotonin is a major cause of migraine, and elevating serotonin’s levels also serves to stop the overproduction of inflammatory brain chemicals like glutamate and CGRP. While lower serotonin levels result in increased receptor sites (as discussed in the benefits section), low serotonin is not a good thing for migraineurs.  Changes in serotonin levels from coffee consumption lead to the “characteristic withdrawal symptoms (such as agitation and irritability) when coffee intake is stopped. The brain has come to expect more action in its serotonin receptors, and when its abundant supply of happy chemicals is abruptly cut off, it gets crabby. . . .” (Source) To help with migraine symptoms, we want to increase serotonin, not inhibit it.
  • “Caffeine produces its stimulant effects by inhibiting the release of GABA and thereby allowing the increase of excitatory neurotransmitters. The less GABA, the more nerve transmissions occur. Think what too much coffee feels like: that is the sensation of glutamate without enough GABA.” (Source) Why this is relevant: migraineurs need to increase their GABA.  They can do so through improved gut health and consumption of prebiotics as outlined in the SimplyWell Migraine Relief Protocol.  Inhibited GABA is not desirable for migraineurs, because it leads to excess glutamate (which in turn leads to excess CGRP, an excitatory neurotransmitter elevated in those with migraine).
  • Coffee inhibits the absorption of iron, as well as vitamin B6 and thiamine.  This is true even in the case of decaf coffee, because the nutrient depletion happens not by way of caffeine, but by way of the tannins in the coffee that bind to these minerals and vitamins.  For this reason, tannins in tea are also problematic and steal B vitamins.  Why this is relevant: Iron and B6 are both involved with the synthesis of serotonin, dopamine, and GABA. B6 is also needed to create Diamine Oxidase (DAO), the enzyme that breaks down histamine. Thiamine is important for the creation of acetylcholine, which is needed for proper vagal tone and to keep inflammation in the body down. Migraineurs are generally anemic and low in these vitamins already.  They need the constituents necessary to produce serotonin, DAO, dopamine, GABA and especially acetylcholine.
  • Increased alertness (or anxiety) due to caffeine may be mainly due to blockage of adenosine receptors which normally inhibit glutamate release. Why this is relevant: migraineurs have high levels of glutamate, which causes excitotoxicity in the brain.  We need our adenosine receptors to be working properly so as to prevent an excessive buildup of glutamate. Glutamate released into synapses is normally reabsorbed back into neurons by the ion-exchange transport system, or soaked-up by astrocytes which convert the glutamate into glutamine (a molecule which cannot cause excitotoxicity). However part of the pathology of migraine is imbalanced electrolyte levels which impact the effectiveness of ion-exchange.
  • Caffeine increases cortisol, adrenaline, and epinephrine, mimicking a state of acute stress. Why this is relevant: stress increases histamine and inflammation, which we all have enough of already.
  • Caffeine is metabolized more slowly in women, especially those on oral contraceptives or postmenopausal hormone replacement therapy, due to the fact that it is detoxified using the same enzyme used to metabolize estrogen. Why this is relevant: more women than men get migraines and many women are on hormone replacement therapy or oral contraceptives.
  • Chronic coffee consumption increases insulin resistance. This typically occurs with a diet high in refined sugars and starches, and many people consume their coffee with pastries or refined carbs. This horrible combination creates inflammation and neurotransmitter imbalances. Why this is relevant: Migraineurs already have imbalanced sugar metabolism and low blood sugar.  We don’t need more.
  • Caffeine decreases vitamin D receptor protein expression (Source).  Why this is relevant: Vitamin D is essential for lowering inflammation, proper digestion, deep sleep, and for serotonin production.
  • Coffee is a diuretic, ie, dehydrating. Why this is relevant: As migraineurs, our kidneys and adrenals are already stressed out from the constant inflammation in our system.  Due to their compromised status, we already excrete important vitamins and minerals like sodium, magnesium, and the B vitamins faster than most people.  And we are already dehydrated.
  • Coffee is acidifying. Why this is relevant: due to having compromised kidney function, most migraineurs also have compromised pH balance (ie, are already acidic).
  • Coffee consumption causes dependency and uncomfortable withdrawal symptoms. “Studies of caffeine dependency and tolerance show that daily caffeine users are actually more motivated to consume it to avoid withdrawal symptoms, than to experience the lift that its stimulant properties may provide.” (Source)
  • “Research has shown that some conditions, such as long-term antibiotic use or excessive consumption of alcohol or caffein can deplete inositol stores. Suboptimal levels of inositol can negatively impact brain function, and memory loss may be an indication of inositol deficiency.” (Source)

The healthiest coffee

The healthiest coffee to drink is cold-brewed, organic water-pressed decaffeinated coffee.  Conventional processes used to decaffeinate coffee use a lot of harmful chemicals.  Decaf coffee contains some caffeine.  And it is still acidifying for the body.  Once you have bought your water-pressed decaf coffee, you can cold brew it according to these instructions here.

Alternately, you can make an herbal “coffee” substitute using healing herbs that actually support digestion, liver health, and adrenal function.  Check out my chicory, dandelion, and chaga “coffee” recipe here.

The ultimate question is always: what does your bodywisdom say about your coffee consumption?

I’ve learned over the years that I actually don’t love coffee.  I love the flavor and ritual of coffee.  And there is something about the joy of doing something that I tell myself I shouldn’t just because it’s fun to live a little, to indulge in life’s pleasures and to counterbalance any tendency towards strict denial in life.  But ultimately I’d rather have a clear head, healthy kidneys, and a happy stomach.  So I only drink coffee about twice a month to remind myself that I don’t actually enjoy the feeling coffee gives me, even while I love the taste.

So what’s the takehome?

Is the occasional cup of coffee going to counterbalance all your efforts to get rid of your migraines?  No. Will occasional cups of coffee actually be supportive to you as someone with migraines?  Yes.  Is the consumption of daily cups of coffee, even decaf coffee, going to undermine all of your other good lifestyle habits?  If you are consuming coffee in excess out of stress, depletion, and a deep sense of fatigue – absolutely. We may want to keep in mind that caffeine is a defensive toxin designed by various plants to repel herbivores from its the berries and seeds. On the other hand, humans evolved eating small amounts of toxic substances which stimulate the liver.

What do the neurologists say about caffeine consumption if you have migraine?

It is important to emphasize that caffeine consumption is rarely the sole “cause” of frequent headaches including migraine. However, it is a modifiable risk factor, unlike many other unavoidable migraine triggers. Caffeine is often a significant and overlooked contributor to the problem of frequent and chronic daily headache. Migraine sufferers should use caffeine less frequently or remove it entirely as one component of a program of therapies for success, and it requires no prescription. (Source)

[author] [author_image timthumb=’on’][/author_image] [author_info]Marya Gendron is a biodynamic craniosacral therapist, health coach, and wellness researcher. She specializes in chronic migraine headache relief and alleviation of brain fog, indigestion, and histamine intolerance through plant-based solutions.

The SimplyWell Protocol is available here, or you can book a consultation with Marya.
Learn more about Marya’s healing journey here.
[/author_info] [/author]

Improve Your Sleep & Brain Health with This Electrolyte Sesame & Honey Recipe

honey for better sleep

Getting better sleep is perhaps the most crucial – and elusive – lifestyle improvement for those with migraine headache.

Without adequate sleep (and especially deep REM sleep), the body and brain can’t repair itself.  Many of us with a history of chronic migraine may not even remember what it feels like to wake up from sleep refreshed and energized.  Instead, most people with migraine will not only have poor sleep and fewer REM deep sleep cycles than healthier people, but migraines will actually start in the middle of the night.  The result is waking up with a headache – a horrible way to start the day.

Some people even wake up very early in the morning – between 1am and 4am with the headache, and never fall deeply back into sleep.  This is because both adrenaline and glutamate levels peak at this time when the brain is starved of proper nutrition and fluid to regenerate. The solution is to give it the proper nutritional support prior to going to bed in the form of sufficient electrolytes, glucose, tryptophan, and GABA-enhancing prebiotics.  All of these ingredients will help to counterbalance the excess cortisol and glutamate that normally peak when the brain is stuck in a dysfunctional circadian rhythm.  For more info on circadian rhythms, check out this article.

My question is always: are there simple culinary Folk Medicine remedies that can help to solve these seemingly intractable problems?  The reason I always ask this question first is because I’ve never found there is NOT a simple, affordable, safe Folk Medicine solution that works as good, but usually better, than pharmaceutical options – which just scramble our fragile systems even more.

As it turns out, honey has long been recognized throughout history for its energy and brain boosting effects.  Now, science is catching up on the explanations for why honeys is so supportive of brain health.

Honey has an appreciable nutritional value. Raw honey possesses anxiolytic, antinociceptive, anticonvulsant, and antidepressant effects and improves the oxidative status of the brain. Several honey supplementation studies suggest that honey polyphenols have neuroprotective and nootropic effects. Polyphenol constituents of honey quench biological reactive oxygen species that cause neurotoxicity and aging as well as the pathological deposition of misfolded proteins, such as amyloid beta. Polyphenol constituents of honey counter oxidative stress by excitotoxins . . . and neurotoxins . . . Raw honey and honey polyphenols attenuate the microglia-induced neuroinflammation that is induced by ischemia-reperfusion injury or immunogenic neurotoxins. Most importantly, honey polyphenols counter neuroinflammation in the hippocampus, a brain structure that is involved in spatial memory. Honey polyphenols also counter memory deficits and induce memory formation at the molecular level. (Source)

From the research I’ve done into sleep and migraine, I’ve created this delicious sleepy-time drink that can be consumed prior to bed and actually works to help establish solid, regenerative sleep.  You won’t find this recipe elsewhere on the web, so if you have any friends with sleep issues, please share this article!

But first, a few lifestyle choices that will act as powerful (and obvious!) leverage points for better sleep:

  1. Limit screen time past 9pm. Turn off your cell phone, get off the computer, turn off the TV.  Why not even turn off your router!  Give yourself a break.  Develop clear boundaries around technology use.
  2. Implement a simple relaxation routine into your evening prior to sleeping.  This could be as simple and variable as taking a hot bath, making the space for mediation or prayer, reading poetry, snuggling with your kids, making love to your Beloved or exchanging massage with them, doing some yoga, or burning some incense (I personally love sweetgrass, palo santo, or cedarwood shavings burnt on charcoal). Anything that relaxes you!
  3. Get outside during the day (or supplement with Vitamin D) and move your body.  Getting both sunlight and exercise improve sleep and serotonin production.  If you can’t get outside, look into vitamin D supplementation.  It’s been shown to be chronically low in people with migraine, and is essential for establishing healthy sleep patterns (and a host of other things, including digestion).  Blood values for vitamin D should be a minimum of 30ng/ml, up to 80ng/ml.  Low vitamin D levels have also been associated with low serotonin levels.
  4. Examine your relationship to caffeine and coffee, and adjust accordingly.  Some of us are so sensitive to caffeine and coffee that drinking a small amount in the early morning can be one reason we have a hard time falling asleep even long after the coffee was consumed.
  5. Take good care of your adrenals. “An effective way to manage chronically elevated cortisol levels is to ensure that the adrenal glands are supported by proper nutrition. Vitamin B6, vitamin B5 (pantothenic acid), and vitamin C often become depleted with prolonged hyperactivity of adrenal gland activity and increased production of cortisol.” (Source).  Most people with migraine are depleted of B6 an B5 because their gut flora have become so dyregulated that the gut flora no longer produce the B vitamins for them, and their ability to absorb the nutrients and cofactors needed to utilize them in food is also compromised.
  6. Reduce your histamine load.  High levels of histamine interfere with sleep.  You can follow a low-histamine diet until you get your histamine overload addressed.

Restorative Sleepytime Drink Recipe

In order to increase blood volume, serotonin, melatonin, GABA, and energy for the brain, our ideal drink would include electrolytes, glucose, tryptophan, and prebiotics.  To make this recipe simple and avoid complicated and lengthy prep time prior to going to bed, you’ll want to prep the milk portion of this recipe and the honey and salt portion separately and have them prepared for easy mixing every night.

Also keep in mind that there is some evidence that tryptophan needs to be consumed prior to the honey for the honey to get the tryptophan into the brain, in which case it is valuable to drink the nutmilk portion throughout the day and the honey portion prior to bed.  However in this case, if drinking the honey with the nutmilk prior to bed is more appealing than the honey/salt alone (whether or not you have had the nutmilk earlier in the day), that is a good option.

This recipe is only for those who tolerate honey, which doesn’t spike insulin levels like other simple carbs. The honey used in this recipe must be organic. Honey can accumulate GMO pollen grains and pesticides. A lot of conventional honey is made from bees fed high fructose corn syrup, and/or is adulterated with high fructose corn syrup. Highest quality is of importance here.  Honey is an amazing food full of 18 amino acids.  It is antibacterial and soothing to the throat and stomach.  Honey raises blood sugar gradually, unlike consumption of refined sugars.

Nutmilk Portion
Sesame seeds are the seeds highest in tryptophan (a precursor to serotonin).  They also contain calcium which helps the body to utilize tryptophan.  Almonds also contain tryptophan as well as magnesium, which aids in sleep.  You can make a nutmilk out of both sesame and almonds, or either of these alone, or experiment with variations on this theme (pumpkin seeds are also high in tryptophan, and shredded coconut contains it as well).

Note: Almonds are expensive and extremely water and labor intensive – they actually have to import bees from New Zealand to pollinate monoculture almond groves.  Therefore, a simple sesame seed nutmilk is the more sustainable option.

Here’s an example of the ratio of almond to sesame seeds that I personally enjoy most:

1/2 cup hulled raw sesame seeds (the majority of the oxalate content is in the hulls, so get unhulled)
1/2 cup of almonds
4 cups of water

Blend on high power and strain through a cheesecloth, nutmilk bag or fine mesh strainer. I personally prefer a mesh strainer even though it requires me to use a clean finger rotated in a circular motion in the strainer to help the nutmilk through. After all the milk has been strained through, I empty the strainer of the larger chunks before pouring the next portion through.  The nutmilk made with a strainer rather than nutmilk bag seems richer and thicker.

Honey & Salt Portion:
1 cup of water warm enough to dissolve honey (but not boiling, to preserve vitamins and enzymes in honey)
2/3 cup of organic raw honey (10 Tablespoons)
2 Tablespoons of Himalayan Pink or Sea Salt

To Make Your Drink Each Night:
Warm or cold, drink the following mixture prior to brushing teeth and going to bed:
1/2- 1 cup of the nutmilk
1 teaspoon of the honey salt mixture
1 teaspoon of resistant potato starch (to feed friendly flora and increase GABA).

This nutmilk recipe is also delicious used throughout the day to keep blood sugar levels up, and not only for consumption prior to bed. In that case you can also just store the mixture in the fridge with all the ingredients already combined, just be sure to agitate the potato starch if you do that, as it tends to settle at the bottom.

Comments are open for this post.  Please let me know how it works for you! Happy Sleeping!

[author] [author_image timthumb=’on’][/author_image] [author_info]Marya Gendron is a biodynamic craniosacral therapist, health coach, and wellness researcher. She specializes in chronic migraine headache relief and alleviation of brain fog, indigestion, and histamine intolerance through plant-based solutions.

The SimplyWell Protocol is available here, or you can book a consultation with Marya.
Learn more about Marya’s healing journey here.
[/author_info] [/author]